Optical spectroscopy is increasingly used for both academic and commercial purposes in the study of biology, including tissue and disease characterization, cellular microanalysis, food inspection, and microbe identification, among others. Raman spectroscopy, in particular, has been used extensively for these biological studies due to its molecular specificity and portable instrumentation. With various instrument options available, systems can be configured to sample from the macro- to micro-scale at multiple wavelengths to avoid intrinsic fluorescence and maximize Raman signal.